WebBromoTAG was developed by Conner Craigon and Adam Bond, PhD students at CeTPD and is a powerful chemical biology tool, enabling the rapid and selective removal of any individual protein. It has been shown to degrade the tagged protein at low concentration, within minutes, and reversibly. WebBromoTag is a novel TAG degradation platform designed to degrade intracellular proteins of interest. The BromoTag system requires the target protein to be expressed as a fusion protein with a TAG protein, called a …
School of Life Sciences, University of Dundee on LinkedIn: #protac …
WebJul 28, 2024 · BromoTAG was developed by Conner Craigon and Adam Bond, PhD students at CeTPD and is a powerful chemical biology tool, enabling the rapid and selective removal of any individual protein. It has been shown to degrade the tagged protein at low concentration, within minutes, and reversibly. Critically, it degrades only the individual … WebThe BromoTag adds to the arsenal of chemical genetic degradation tools allowing us to manipulate protein levels to interrogate the biological function and therapeutic potential in … clear sky draught haus clearwater
Bio-Techne Announces Licensing Agreement with University of …
WebOct 15, 2024 · Development of BromoTag: A "Bump-and-Hole"-PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins. Adam G Bond Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, U.K. Author profile Search articles by ORCID WebBromoTag is a novel TAG degradation platform designed to degrade intracellular proteins of interest. The BromoTag system requires the target protein to be expressed as a … WebThe BromoTag adds to the arsenal of chemical genetic degradation tools allowing us to manipulate protein levels to interrogate the biological function and therapeutic potential in cells and in vivo. blue sky waxing bentonville ar