WebWe found that the dynamics of striatal neurons predicted duration judgments, and that simultaneously recorded ensembles could judge duration as well as the animal. Furthermore, striatal neurons were necessary for duration judgments, as muscimol infusions produced a specific impairment in animals' duration sensitivity. WebJun 15, 2015 · These results demonstrate that striatal dynamics form an internal “neural population clock”16-17 that supports the fundamental ability of animals to judge the passage of time. To measure the duration sensitivity of subjects’ timing judgments, we trained rats to judge whether time intervals belonged to a long or short category18 (see ...
(PDF) Striatal dynamics explain duration judgments
WebAug 12, 2024 · The perception of time is critical to adaptive behavior. While prefrontal cortex and basal ganglia have been implicated in interval timing in the seconds to minutes range, little is known about the role of the mediodorsal thalamus (MD), which is a key component of the limbic cortico–basal ganglia–thalamocortical loop. In this study, we tested the role of … Webof population dynamics: faster dynamics were correlated with longer duration judgments and vice-versa. To directly assess whether variability in the speed of striatal population dynamics causes variability in duration judgments, we experimentally manipulated striatal temperature during task performance using a custom-made thermoelectric device. take-two interactive software inc. stock
Neural Sequences as an Optimal Dynamical Regime for the Readout of Time …
WebStriatal dynamics explain duration judgments. eLife. 2015; 4: e11386. View in Article Scopus (80) PubMed; Crossref; Google Scholar; Hahnloser R.H.R. Kozhevnikov A.A. Fee M.S. An ultra-sparse code underlies the generation of neural sequences in a songbird. Nature. 2002; 419: 65-70. View in Article ... WebThe ability to estimate the passage of time is essential for adaptive behavior in complex environments. Yet, it is not known how the brain encodes time over the durations necessary to explain animal behavior. Under temporally structured reinforcement schedules, animals tend to develop temporally structured behavior, and interval timing has been ... WebStriatal dynamics explain duration judgments Preprint Full-text available Sep 2015 Thiago Gouvêa Tiago Monteiro Asma Motiwala [...] Joe Paton The striatum is an input structure of the basal... twitch offline banner free erstellen