Teprasiran sodium
WebTEPRASIRAN SODIUM [USAN] Source: Common Name English Code System Code Type Description; FDA UNII: ME0IRL7KDY Created by admin on Sat Jun 26 18:53:34 UTC … WebApr 27, 2024 · Drug: teprasiran Drug: Placebo: Phase 3: Detailed Description: This is a randomized, double-blind, placebo-controlled, Phase 3 trial to evaluate QPI-1002 versus …
Teprasiran sodium
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WebMay 17, 2024 · Sodium plays a key role in your body. It helps maintain normal blood pressure, supports the work of your nerves and muscles, and regulates your body's fluid … WebSep 16, 2024 · Teprasiran is a small interfering RNA that can temporarily inhibit p53-mediated cell death, which may be involved in acute kidney injury (AKI) seen after cardiac surgery requiring cardiopulmonary bypass. The authors evaluated the safety and efficacy of teprasiran for preventing AKI in high-risk cardiac surgery patients.
WebTEPRASIRAN SODIUM [USAN] Common Name; UNII Resources. Common Chemistry CAS Common Chemistry is an open community resource of the American Chemical … WebApr 1, 2016 · Teprasiran is a novel small interfering RNA (siRNA) that temporarily inhibits p53-mediated cell death, which underlies AKI. ... Sodium bicarbonate increased plasma bicarbonate (P < 0.001) and ...
WebNCT03510897: Phase 3 Interventional Active, not recruiting Cardiac Surgery (2024) WebSep 3, 2024 · Teprasiran is a novel small interfering RNA (siRNA) that temporarily inhibits p53-mediated cell death, which underlies AKI. Methods: This prospective, multicenter, …
WebJan 14, 2024 · CAS No. : 1499251-18-1 Biological Activity： Fitusiran (ALN-AT3SC), an small interfering RNA, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. Fitusiran increases thrombin generation and has the potential for the research of the hemophilia. Research Area：Others
WebTEPRASIRAN SODIUM September 26, 2024 M18 Page 1 of 1 155 . STATEMENT ON A NONPROPRIETARY NAME ADOPTED BY THE USAN COUNCIL . USAN (fg-143) … st george\u0027s kemptown brightonWebTEPRASIRAN SODIUM [USAN] Resources. ChemIDplus; DrugPortal; NCI Thesaurus; Note. UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. st george\u0027s house wolverhampton probationWebSep 3, 2024 · AKI severity and duration were also improved with teprasiran: 2.5% of teprasiran vs. 6.7% of placebo-treated patients had Grade 3 AKI; 7% teprasiran vs. 13% placebo-treated patients had AKI lasting for 5 days. No significant difference was observed for the MAKE90 composite in the overall population. st george\u0027s maternity wardWebJan 11, 2024 · For research use only. We do not sell to patients. Lumasiran sodium. CAS No. : 1834612-06-4. Biological Activity：Lumasiran sodium, an investigational RNA interference (RNAi) therapeutic agent, reduces hepatic oxalate production by targeting glycolate oxidase.Lumasiran sodium reduces urinary oxalate excretion, the cause of … st george\u0027s medical centre new brightonWebMay 17, 2024 · Hyponatremia treatment is aimed at addressing the underlying cause, if possible. If you have moderate, chronic hyponatremia due to your diet, diuretics or drinking too much water, your doctor may recommend temporarily cutting back on fluids. He or she may also suggest adjusting your diuretic use to increase the level of sodium in your blood. st george\u0027s lymphoedema clinicWebSep 3, 2024 · The incidence, severity, and duration of early AKI in high-risk patients undergoing cardiac surgery were significantly reduced after teprasiran administration. Supplemental Digital Content is available in the text. Background: Acute kidney injury (AKI) affects up to 30% of patients undergoing cardiac surgery, leading to increased in-hospital … st george\u0027s london ontarioWebMay 20, 2024 · Generic Name Teprasiran DrugBank Accession Number DB15064 Background Teprasiran is under investigation in clinical trial NCT03510897 (QPI-1002 … st george\u0027s library opening times